It is a distinctive form of NANB hepatitis, characterized by faeco-oral transmission and a short incubation period of about 6 weeks.
Disease is of self limited natureoccuring either sporadic or n the form of epidemics. It affects mainly young adults.
There is little riskof development of chronic hepatitis, but there is high mortality rate due to disseminated intravascular coagulation especially in pregnant females.
Diagnosis
a)PCR is used to detect viral RNA in stools.
b) Detection of anti-hepatitis E virus IgM and IgG by ELISA.
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