PYREXIA OF UNDETERMINED ORIGIN(PUO)

Major causes of PUO
1. Infections
2. Neoplasms
3. Autoimmune diseases as systemic lupus and rheumatic fever
4. Drug induced fever
5. Granulomatous disease

Infective causes of PUO

A- Non specific causes:


B-Specific causes

bacteria

-tuberculosis
-leptospirosis
-typhoid
-relapsing fever
-brucellosis
-Q fever
-Typhus
-Nocardiosis

virus

-hepatitis A or B
-yellow fever
-cytomegalovirus
-HIV infection AIDS
-Lassa fever
- Infectious mononucleosis

fungi

-Cryptococcis
-Histoplasmosis
-Candidiasis
-Aspergillosis
-Penumocystis